Frailty and the Selection of Patients for Destination Therapy Left Ventricular Assist Device

Frailty and the selection of patients for destination therapy left ventricular assist device.

Advances in Heart Failure Frailty and the Selection of Patients for Destination Therapy Left Ventricular Assist Device

F railty is the aggregation of subclinical physiological insults across many organ systems resulting in a syndrome of heightened vulnerability in the face of stress. Measures of frailty are highly predictive of adverse outcomes in many medical and surgical populations but have never been formally applied to patient selection for destination therapy left ventricular assist device (LVAD). Patient...

Dying With a Left Ventricular Assist Device as Destination Therapy.

BACKGROUND Despite the ability of left ventricular assist device as destination therapy (DT-LVAD) to prolong survival for many patients with advanced heart failure, little is known about the eventual end-of-life care that patients with DT-LVAD receive. METHODS AND RESULTS All patients undergoing DT-LVAD at the Mayo Clinic in Rochester, Minnesota, from January 1, 2007, to September 30, 2014, w...

Left ventricular assist devices as destination therapy.

Although an estimated 16,500 Americans annually could benefit from a heart transplant, in 1999 only 2184 heart transplants were performed in the United States. These statistics emphasize the severity of the shortage of available hearts for transplantation. Circulatory support provided by an implantable Left Ventricular Assist Device (LVAD) that meets Food and Drug Administration approval as des...

Patients' and caregivers' inside perspectives: living with a left-ventricular assist device as destination therapy

PATIENTS’ AND CAREGIVERS’ INSIDE PERSPECTIVES: LIVING WITH A LEFT-VENTRICULAR ASSIST DEVICE AS DT